When the seaside community of Amity finds itself under attack by a dangerous great white shark, the town's chief of police, a young marine biologist, and a grizzled shark hunter embark on a desperate quest to kill the beast before it strikes again.

Dr. Frankenstein and his monster both turn out to be alive after being attacked by an angry mob. The now-chastened scientist attempts to escape his past, but a former mentor forces him to assist with the creation of a new creature.